Product Datasheet
OXCT1 Antibody
Catalog Number: 36673
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P55809
NCBI Gene ID: 5019
Gene Accssion: BC009001/P55809
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human 3-oxoacid CoA transferase 1
- appl_detail:
- Western blotting: 1:500-1:2000
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total OXCT1 protein.
- Background:
- This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.
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