Product Datasheet  
OS9 Antibody  
Catalog Number: 36669  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q13438
    NCBI Gene ID: 10956
    Gene Accssion: BC007254
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Fusion protein corresponding to a region derived from internal residues of human osteosarcoma amplified 9, endoplasmic reticulum lectin
  • reactivity:  
  • Hu Ms
  • appl_detail:  
  • Western blotting: 1:500-1:2000
  • other_names:  
  • OS-9; ERLEC2
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total OS9 protein.
  • Applications:  
  • WB
  • Background:  
  • This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.



 
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