Product Datasheet
OS9 Antibody
Catalog Number: 36669
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q13438
NCBI Gene ID: 10956
Gene Accssion: BC007254
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human osteosarcoma amplified 9, endoplasmic reticulum lectin
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- OS-9; ERLEC2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total OS9 protein.
- Background:
- This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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