Product Datasheet
NR1D1 Antibody
Catalog Number: 36659
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P20393
NCBI Gene ID: 9572
Gene Accssion: BC047875/P20393
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the N terminal of human nuclear receptor subfamily 1, group D, member 1
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- EAR1; hRev; THRA1; THRAL; ear-1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NR1D1 protein.
- Background:
- This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes.?
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