Product Datasheet
PVRL3 Antibody
Catalog Number: 36648
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9NQS3
NCBI Gene ID: 25945
Gene Accssion: BC067808/Q9NQS3
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human poliovirus receptor-related 3
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200
- other_names:
- PPR3; PRR3; CD113; PVRR3; CDW113; NECTIN-3
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PVRL3 protein.
- Background:
- This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants.
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