Product Datasheet
NDUFS4 Antibody
Catalog Number: 36643
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O43181
NCBI Gene ID: 4724
Gene Accssion: BC005270/O43181
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NDUFS4 protein.
- Background:
- This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane.
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