Product Datasheet
NDUFA1 Antibody
Catalog Number: 36636
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O15239
NCBI Gene ID: 4694
Gene Accssion: BC000266
- Form of Antibody:
- Rabbit IgG in PBS with 0.02% sodium azide,50% glycerol,pH7.3.
- Immunogen:
- Recombinant fusion protein
- other_names:
- MWFE; ZNF183; CI-MWFE
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NDUFA1 protein.
- Background:
The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane.?
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