Product Datasheet
NBL1 Antibody
Catalog Number: 36632
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P41271
NCBI Gene ID: 4681
Gene Accssion: NP_005371
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human neuroblastoma 1, DAN family BMP antagonist
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- NB; DAN; NO3; DAND1; D1S1733E
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NBL1 protein.
- Background:
- This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development.?
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