Product Datasheet
MATR3 Antibody
Catalog Number: 36602
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P43243
NCBI Gene ID: 9782
Gene Accssion: BC015031/P43243
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the N terminal of human matrin 3
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- MPD2; ALS21; VCPDM
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MATR3 protein.
- Background:
- This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Mutations of this gene are associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts composed of the upstream small nucleolar RNA host gene 4 (non-protein coding) and matrin 3 gene sequence, have been identified. Pseudogenes of this gene are located on chromosomes 1 and X.
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