Product Datasheet
LEPREL2 Antibody
Catalog Number: 36584
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8IVL6
NCBI Gene ID: 10536
Gene Accssion: BC017217
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human leprecan-like 2
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
- other_names:
- GRCB; P3H3; HSU47926
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total LEPREL2 protein.
- Background:
- The protein encoded by this gene belongs to the leprecan family of proteoglycans, which function as collagen prolyl hydroxylases that are required for proper collagen biosynthesis, folding and assembly. This protein, like other family members, is thought to reside in the endoplasmic reticulum. Epigenetic inactivation of this gene is associated with breast and other cancers, suggesting that it may function as a tumor suppressor.
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