Product Datasheet  
KLK6 Antibody  
Catalog Number: 36575  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q92876
    NCBI Gene ID: 5653
    Gene Accssion: BC015525
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein corresponding to a region derived from internal residues of human kallikrein-related peptidase 6
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500-1:2000
    Immunohistochemistry: 1:100-1:300
  • other_names：  
  • hK6; Bssp; Klk7; SP59; PRSS9; PRSS18
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total KLK6 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.



 
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