Product Datasheet
IRGM Antibody
Catalog Number: 36558
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: A1A4Y4
NCBI Gene ID: 345611
Gene Accssion: BC128168
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200
- other_names:
- IFI1; IRGM1; LRG47; LRG-47
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total IRGM protein.
- Background:
- This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis.
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