Product Datasheet
AKR1C4 Antibody
Catalog Number: 36535
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P17516
NCBI Gene ID: 1109
Gene Accssion: BC020744/P17516
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- C11; CDR; DD4; CHDR; DD-4; HAKRA; 3-alpha-HSD
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total AKR1C4 protein.
- Background:
- This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver.?
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