Product Datasheet
HSD17B6 Antibody
Catalog Number: 36533
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O14756
NCBI Gene ID: 8630
Gene Accssion: BC020710
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human hydroxysteroid (17-beta) dehydrogenase 6
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- HSE; RODH; SDR9C6
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total HSD17B6 protein.
- Background:
- The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family.
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