Product Datasheet
HSD17B4 Antibody
Catalog Number: 36531
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P51659
NCBI Gene ID: 3295
Gene Accssion: BC003098
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human hydroxysteroid (17-beta) dehydrogenase 4
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- DBP; MFE-2; MPF-2; PRLTS1; SDR8C1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total HSD17B4 protein.
- Background:
- The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8.?
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