Product Datasheet
HIST4H4 Antibody
Catalog Number: 36519
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P62805
NCBI Gene ID: 8359
Gene Accssion: NP_003529
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human histone cluster 4, H4
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total HIST4H4 protein.
- Background:
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element.
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