Product Datasheet
PPAT Antibody
Catalog Number: 36506
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q06203
NCBI Gene ID: 5471
Gene Accssion: BC004200
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human phosphoribosyl pyrophosphate amidotransferase
- appl_detail:
- Immunohistochemistry: 1:100-1:300
- other_names:
- GPAT; PRAT; ATASE
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PPAT protein.
- Background:
- The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region.
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