Product Datasheet
GLIPR1 Antibody
Catalog Number: 36505
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P48060
NCBI Gene ID: 11010
Gene Accssion: BC012510
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human GLI pathogenesis-related 1
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:100-1:300
- other_names:
- GLIPR; RTVP1; CRISP7
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total GLIPR1 protein.
- Background:
- This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
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