Product Datasheet
Histone H4R3me1 Polyclonal Antibody
Catalog Number: HW026
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Gene ID: 8290 Swiss Prot: P62805
NCBI Gene ID:121504
- Form of Antibody:
- Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- Storage:
- Store at -20�?or -80�? Avoid freeze / thaw cycles.
- Immunogen:
- A synthetic peptide corresponding to the amino terminus of histone H4 in which Arg3 is mono-methylated.
- appl_detail:
WB 1:500 - 1:2000
- other_names:
- HIST1H4A; H4/A; H4FA; HIST1H4B; H4/I; H4FI; HIST1H4C; H4/G; H4FG; HIST1H4D; H4/B; H4FB; HIST1H4E; H4/J; H4FJ; HIST1H4F; H4/C; H4FC; HIST1H4H; H4/H; H4FH; HIST1H4I; H4/M; H4FM; HIST1H4J; H4/E; H4FE; HIST1H4K; H4/D; H4FD; HIST1H4L; H4/K; H4FK; HIST2H4A; H4/
- Purification:
- Antibodies were produced by immunizing rabbits and were purified by antigen affinity-chromatography.
- Background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.
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