Product Datasheet
FCGR2B Antibody
Catalog Number: 36473
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P31994
NCBI Gene ID: 2213
Gene Accssion: BC031992
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human Fc fragment of IgG, low affinity IIb, receptor (CD32)
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
- other_names:
- CD32; FCG2; CD32B; FCGR2; IGFR2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total FCGR2B protein.
- Background:
- The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
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