Product Datasheet
FADS1 Antibody
Catalog Number: 36457
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O60427
NCBI Gene ID: 3992
Gene Accssion: BC007846
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human fatty acid desaturase 1
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:100-1:300
- other_names:
- D5D; TU12; FADS6; FADSD5; LLCDL1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total FADS1 protein.
- Background:
- The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.
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