Product Datasheet
EPSTI1 Antibody
Catalog Number: 36445
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q96J88
NCBI Gene ID: 94240
Gene Accssion: BC023660
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the N terminal of human epithelial stromal interaction 1
- appl_detail:
- Western blotting: 1:1000-1:5000
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total EPSTI1 protein.
- Background:
- EPSTI1 (Epithelial-stromal interaction protein 1), also known as BRESI1, is a 318 amino acid protein that is highly expressed in spleen, placenta, small intestine, liver, kidney, thymus, testis and salivary gland. Existing as three isoforms that are formed due to alternative splicing events, EPSTI1 is weakly expressed in normal breast tissue, but is heavily up-regulated in breast carcinoma, suggesting an important role for EPSTI1 in tumor formation and/or progression. Additionally, EPSTI1 is found in blood cells from systemic lupus erythematosus (SLE)-afflicted patients, implicating EPSTI1 as a potential protein involved in SLE.
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