Product Datasheet
DNASE1L3 Antibody
Catalog Number: 36420
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q13609
NCBI Gene ID: 1776
Gene Accssion: BC015831
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human deoxyribonuclease I-like 3
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- LSD; DHP2; SLEB16; DNAS1L3
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total DNASE1L3 protein.
- Background:
- This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.?
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