Product Datasheet
DEGS1 Antibody
Catalog Number: 36411
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O15121
NCBI Gene ID: 8560
Gene Accssion: BC000961
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human delta(4)-desaturase, sphingolipid 1
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:100-1:300
- other_names:
- MLD; DEGS; DES1; Des-1; FADS7; MIG15; DEGS-1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total DEGS1 protein.
- Background:
- This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.
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