Product Datasheet  
DEGS1 Antibody  
Catalog Number: 36411  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: O15121
    NCBI Gene ID: 8560
    Gene Accssion: BC000961
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Fusion protein corresponding to a region derived from internal residues of human delta(4)-desaturase, sphingolipid 1
  • reactivity:  
  • Hu Ms
  • appl_detail:  
  • Western blotting: 1:200-1:1000
    Immunohistochemistry: 1:100-1:300
  • other_names:  
  • MLD; DEGS; DES1; Des-1; FADS7; MIG15; DEGS-1
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total DEGS1 protein.
  • Applications:  
  • WB IHC
  • Background:  
  • This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.



 
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