Product Datasheet
DACH2 Antibody
Catalog Number: 36397
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q96NX9
NCBI Gene ID: 117154
Gene Accssion: BC114950
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human dachshund homolog 2 (Drosophila)
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- FLJ31391;MGC138545;Dachshund homolog 2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total DACH2 protein.
- Background:
- This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene.?
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