Product Datasheet
CENPH Antibody
Catalog Number: 36339
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9H3R5
NCBI Gene ID: 64946
Gene Accssion: BC012024
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- CENP-H; ICEN35;Centromere protein H
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CENPH protein.
- Background:
- Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C.?
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