Product Datasheet
SPN Antibody
Catalog Number: 36332
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P16150
NCBI Gene ID: 6693
Gene Accssion: BC012350
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human sialophorin
- appl_detail:
- Immunohistochemistry: 1:100-1:300
- other_names:
- LSN; CD43; GALGP; GPL115
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SPN protein.
- Background:
- The protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It may be part of a physiologic ligand-receptor complex involved in T-cell activation. During T-cell activation, this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site, suggesting a negative regulatory role in adaptive immune response.
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