Product Datasheet
NCR3 Antibody
Catalog Number: 36330
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O14931
NCBI Gene ID: 259197
Gene Accssion: BC052582
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human natural cytotoxicity triggering receptor 3
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- 1C7; MALS; CD337; LY117; NKp30
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NCR3 protein.
- Background:
- The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.
© Signalway Biotechnology All Rights Reserved.