Product Datasheet
SLAMF1 Antibody
Catalog Number: 36320
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q13291
NCBI Gene ID: 6504
Gene Accssion: BC067847/Q13291
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the N terminal of human signaling lymphocytic activation molecule family member 1
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- SLAM; CD150; CDw150
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SLAMF1 protein.
- Background:
- High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
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