Product Datasheet
TNFRSF9 Antibody
Catalog Number: 36319
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q07011
NCBI Gene ID: 3604
Gene Accssion: BC006196
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human tumor necrosis factor receptor superfamily, member 9
- other_names:
- ILA; 4-1BB; CD137; CDw137
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TNFRSF9 protein.
- Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.?
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