Product Datasheet
CAT Antibody
Catalog Number: 36312
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P04040
NCBI Gene ID: 847
Gene Accssion: BC110398
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human catalase
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
- other_names:
- CATA;Catalase;MGC138422
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CAT protein.
- Background:
- This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers.
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