Product Datasheet
TP53BP2 Antibody
Catalog Number: 36266
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q13625
NCBI Gene ID: 7159
Gene Accssion: BC040247
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human tumor protein p53 binding protein, 2
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
- other_names:
- BBP; 53BP2; ASPP2; P53BP2; PPP1R13A
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TP53BP2 protein.
- Background:
- This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.
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