Product Datasheet
ASAH2 Antibody
Catalog Number: 36240
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9NR71
NCBI Gene ID: 56624
Gene Accssion: BC107105
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- HNAC1; BCDase; LCDase; NCDase; N-CDase
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ASAH2 protein.
- Background:
- Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger.
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