Product Datasheet  
PIP5K1B Antibody  
Catalog Number: 36234  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: O14986
    NCBI Gene ID: 8395
    Gene Accssion: BC030587
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein corresponding to a region derived from internal residues of human phosphatidylinositol-4-phosphate 5-kinase, type I, beta
  • reactivity：  
  • Hu
  • appl_detail：  
  • Immunohistochemistry: 1:50-1:200
  • other_names：  
  • MSS4; STM7
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total PIP5K1B protein.
  • Applications：  
  • IHC
  • Background：  
  • Phosphatidylinositol-4-phosphate-5-kinase (PIPK) synthesizes phosphatidylinositol-4,5-bisphosphate, which regulates various processes including cell proliferation, survival, membrane trafficking, and cytoskeletal organization. The PIPK family is divided into type I, type II and type III . Each type of the PIPK family phosphorylate distinct substrates and they contain an activation loop, which determines their enzymatic specificity and subcellular targeting . The phosphatidylinositol-4-phosphate-5-kinase type I consists of three members, PIPK I ?, ¡Ò, and ?, which are characterized by phosphorylating PI4P on the 5-hydroxyl . PIPK I ? (designated PIPK I ¡Ò in mouse) is expressed in brain tissue . PIPK I ¡Ò, designated PIPK I a in mouse, is also called STM7. PIPK I ? has two variants produced by alternative splicing which are expressed in lung, brain, and kidneys.



 
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