Product Datasheet
MTMR7 Antibody
Catalog Number: 36184
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9Y216
NCBI Gene ID: 9108
Gene Accssion: BC130579
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human myotubularin related protein 7
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- DKFZp781E194;MGC163449;MGC163451
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MTMR7 protein.
- Background:
- This gene encodes a member of the myotubularin family of tyrosine/dual-specificity phosphatases. The encoded protein is characterized by four distinct domains that are conserved among all members of the myotubularin family: the glucosyltransferase, Rab-like GTPase activator and myotubularins domain, the Rac-induced recruitment domain, the protein tyrosine phosphatases and dual-specificity phosphatases domain and the suppressor of variegation 3-9, enhancer-of-zeste, and trithorax interaction domain. This protein dephosphorylates the target substrates phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate. A pseudogene of this gene is found on chromosome 5.
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