Product Datasheet
ZWINT Antibody
Catalog Number: 36183
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O95229
NCBI Gene ID: 11130
Gene Accssion: BC020979
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- ZWINT1; KNTC2AP; HZwint-1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ZWINT protein.
- Background:
- This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.?
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