Product Datasheet
NRG4 Antibody
Catalog Number: 36182
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8WWG1
NCBI Gene ID: 145957
Gene Accssion: BC017568
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the N terminal of human neuregulin 4
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NRG4 protein.
- Background:
- Neuregulin 4?also known as?NRG4?is a member of the?neuregulin?protein?family which in humans is encoded by theNRG4?gene. Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors.
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