Product Datasheet
PAPSS1 Antibody
Catalog Number: 36177
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O43252
NCBI Gene ID: 9061
Gene Accssion: BC050627
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human 3'-phosphoadenosine 5'-phosphosulfate synthase 1
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- SK1; PAPSS; ATPSK1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PAPSS1 protein.
- Background:
- Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes (Xu et al., 2000 [PubMed 10679223]). SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2.
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