Product Datasheet
INTS10 Antibody
Catalog Number: 36159
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9NVR2
NCBI Gene ID: 55174
Gene Accssion: BC001915
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human integrator complex subunit 10
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200
- other_names:
- INT10; C8orf35
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total INTS10 protein.
- Background:
- INTS10 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit and mediates 3-prime end processing of small nuclear RNAs U1. INTS10 (integrator complex subunit 10) is also known as INT10 and is a 710 amino acid protein that is localized to the nucleus. INTS10 is a component of the integrator complex and, as such, is thought to aid in the regulation of 3¡¯-end processing of spliceosomal U1 and U2 snRNAs.
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