Product Datasheet
ARHGAP1 Antibody
Catalog Number: 36129
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q07960
NCBI Gene ID: 392
Gene Accssion: BC018118
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human Rho GTPase activating protein 1
- appl_detail:
- Immunohistochemistry: 1:15-1:50
- other_names:
- RHOGAP; RHOGAP1; CDC42GAP; p50rhoGAP
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ARHGAP1 protein.
- Background:
- This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein contains a SRC homology 3 domain and interacts with Bcl-2-associated protein family members. GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate.
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