Product Datasheet
NAPSA Antibody
Catalog Number: 36123
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O96009
NCBI Gene ID: 9476
Gene Accssion: BC017842
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human napsin A aspartic peptidase
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
- other_names:
- KAP; Kdap; NAP1; NAPA; SNAPA
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NAPSA protein.
- Background:
- The activation peptides of aspartic proteinases plays role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional, glycosylated aspartic proteinase precursor containing an RGD motif and an additional 18 residues at its C-terminus.
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