Product Datasheet  
FTO Antibody  
Catalog Number: 36489  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q9C0B1
    NCBI Gene ID: 79068
    Gene Accssion: BC003583
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Full length fusion protein
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:500-1:2000
    Immunohistochemistry: 1:100-1:300
  • other_names:  
  • ALKBH9
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total FTO protein.
  • Applications:  
  • WB IHC
  • Background:  
  • This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.



 
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