Product Datasheet
FTO Antibody
Catalog Number: 36489
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9C0B1
NCBI Gene ID: 79068
Gene Accssion: BC003583
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:100-1:300
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total FTO protein.
- Background:
- This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
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