Product Datasheet
COL4A3BP Antibody
Catalog Number: 36362
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9Y5P4
NCBI Gene ID: 10087
Gene Accssion: BC000102
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:100-1:300
- other_names:
- CERT; GPBP; CERTL; STARD11
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total COL4A3BP protein.
- Background:
- This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene.
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