Product Datasheet
AES Antibody
Catalog Number: 36095
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q08117
NCBI Gene ID: 166
Gene Accssion: BC113735
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the N terminal of human amino-terminal enhancer of split
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- GRG; ESP1; GRG5; TLE5; AES-1; AES-2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total AES protein.
- Background:
- The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.
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