Product Datasheet
AMHR2 Antibody
Catalog Number: 36093
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q16671
NCBI Gene ID: 269
Gene Accssion: BC126316
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human anti-Mullerian hormone receptor, type II
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- AMHR; MRII; MISR2; MISRII
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total AMHR2 protein.
- Background:
- This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.
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