Product Datasheet
ALG12 Antibody
Catalog Number: 36079
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9BV10
NCBI Gene ID: 79087
Gene Accssion: BC001729
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human ALG12, alpha-1,6-mannosyltransferase
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- CDG1G; ECM39; hALG12; PP14673
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ALG12 protein.
- Background:
- This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation.
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