Product Datasheet
ALAS2 Antibody
Catalog Number: 36074
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P22557
NCBI Gene ID: 212
Gene Accssion: BC030230
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human aminolevulinate, delta-, synthase 2
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- ASB; ANH1; XLSA; ALASE; XLDPP; XLEPP; ALAS-E
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ALAS2 protein.
- Background:
- The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
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