Product Datasheet
ABCE1 Antibody
Catalog Number: 36004
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P61221
NCBI Gene ID: 6059
Gene Accssion: BC016283
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human ATP-binding cassette, sub-family E (OABP), member 1
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- RLI; OABP; ABC38; RNS4I; RNASEL1; RNASELI
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ABCE1 protein.
- Background:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.
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