Product Datasheet  
ABCE1 Antibody  
Catalog Number: 36004  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: P61221
    NCBI Gene ID: 6059
    Gene Accssion: BC016283
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Fusion protein corresponding to a region derived from internal residues of human ATP-binding cassette, sub-family E (OABP), member 1
  • reactivity:  
  • Hu Ms
  • appl_detail:  
  • Western blotting: 1:500-1:2000
  • other_names:  
  • RLI; OABP; ABC38; RNS4I; RNASEL1; RNASELI
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total ABCE1 protein.
  • Applications:  
  • WB
  • Background:  
  • The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.



 
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