Product Datasheet
VANGL1 Antibody
Catalog Number: 35999
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8TAA9
NCBI Gene ID: 81839
Gene Accssion: BC065272
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human VANGL planar cell polarity protein 1
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- LPP2; STB2; STBM2; KITENIN
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total VANGL1 protein.
- Background:
- This gene encodes a member of the tretraspanin family. The encoded protein may be involved in mediating intestinal trefoil factor induced wound healing in the intestinal mucosa. Mutations in this gene are associated with neural tube defects. Alternate splicing results in multiple transcript variants. Interacts through its C-terminal region with the N-terminal half of DVL1, DVL2 and DVL3. The PDZ domain of DVL1, DVL2 and DVL3 is required for the interaction.
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