Product Datasheet  
SUFU Antibody  
Catalog Number: 35993  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q9UMX1
    NCBI Gene ID: 51684
    Gene Accssion: BC013291
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Fusion protein corresponding to residues near the C terminal of human Suppressor of fused homolog (Drosophila)
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:200-1:1000
    Immunohistochemistry: 1:15-1:50
  • other_names:  
  • SUFUH; SUFUXL; PRO1280
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total SUFU protein.
  • Applications:  
  • WB IHC
  • Background:  
  • The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.



 
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