Product Datasheet
SUFU Antibody
Catalog Number: 35993
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9UMX1
NCBI Gene ID: 51684
Gene Accssion: BC013291
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human Suppressor of fused homolog (Drosophila)
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:15-1:50
- other_names:
- SUFUH; SUFUXL; PRO1280
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SUFU protein.
- Background:
- The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.
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