Product Datasheet
IL18RAP Antibody
Catalog Number: 35987
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O95256
NCBI Gene ID: 8807
Gene Accssion: BC106765
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human Interleukin 18 receptor accessory protein
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- ACPL; CD218b; IL18RB; CDw218b
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total IL18RAP protein.
- Background:
- Interleukin 18 receptor accessory protein, also known as?IL18RAP?and?CDw218b?(cluster of differentiationw218b), is a human?gene. The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-κB and MAPK8 (JNK) in response to IL18.
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